-no one ever thinks to show you how to bowl/hit a baseball/play tennis/etc. left handed, so you end up being taught the right handed way, and are more likely to suck at it.
-you can’t use those eraseable pens.
-you must use scissors with your right hand unless you have some of those crazy hard-to-get left handed scissors.

There was some cognitive research that showed that the right and left hemispheres of left handers’ brains were more tightly integrated. They posited that this is why left handers were better at tasks that required both right and left brain function (e.g., music) but were more accident-prone, as their more intetrated brains were not as good at multi-tasking.

Note that both Jon Stewart and Barack Obama are left handed. That’s good enough for me.

“Left-handers are wired into the artistic half of the brain, which makes them imaginative, creative, surprising, ambiguous, exasperating, stubborn, emotional, witty, obsessive, infuriating, delightful, original, but never, never, dull.”

That was written by James T deKay and Sandy Huffaker in their book called The World’s Greatest Left-Handers: Why Left-Handers are Just Plain Better than Everybody Else

Carole from http://www.thelefthandedsite.com